Description

Cobinamide Dicyanide is a chemically defined, high-purity derivative of vitamin B12, distinguished by its dicyano axial ligands. This compound serves as a critical intermediate and reference standard in the synthesis and analytical characterization of cobalamin-related molecules. It is essential for researchers and manufacturers in the pharmaceutical, diagnostic, and advanced biochemical sectors who require precise and reliable cobinamide derivatives for their processes.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of various therapeutic cobalamin analogs and vitamin B12 derivatives.
• Biochemical Research: Used as a reference standard and model compound for studying cobalamin biochemistry, enzyme cofactors, and corrinoid chemistry.
• Diagnostic Reagents: Employed in the development and calibration of diagnostic assays and kits for vitamin B12 deficiency and related metabolic disorders.
• Nutritional Science: Serves as a controlled compound in studies investigating cobalamin absorption, metabolism, and bioavailability.
• Microbiology: Utilized in microbial growth media and research involving microorganisms that synthesize or require corrinoids.

Basic Information

Product Name	Cobinamide Dicyanide
CAS No.	27792-36-5
Molecular Formula	C53H84CoN14O14P
Molecular Weight	1223.22 g/mol
Synonyms	Dicyanocobinamide; Cob(II)inamide dicyanide; Vitamin B12 dicyanide derivative; Cobinamide, dicyano-; Coβ-cyano-α-(5,6-dimethylbenzimidazolyl)-Coα-(cyano)cobamide; Factor B dicyanide; B12 dicyanide analog
EINECS	Contact for details

Quality Control

Our Cobinamide Dicyanide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and UV-Vis for identification, and residual solvent analysis, to ensure it meets stringent specifications for research and manufacturing use. Certificates of Analysis (COA) documenting all test results are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	Dark red to brownish-red crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (UV-Vis)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.