Description

1-Pyrenyl -D-Glucopyranosiduronic Acid Methyl Ester is a high-purity, fluorescent-labeled biochemical reagent primarily used as a critical substrate and probe in advanced enzymatic and analytical research. This compound matters for its role in studying glucuronidation processes, a key metabolic pathway for detoxification and drug metabolism. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require reliable, well-characterized tools for enzyme activity assays, metabolic pathway analysis, and fluorescence-based detection methods.

Application

• Enzyme Substrate for Glucuronosyltransferases (UGTs): A key reagent for in vitro assays to study the activity, kinetics, and inhibition of UGT enzymes, crucial in drug metabolism and toxicology research.
• Fluorescent Probe Development: Serves as a building block for creating sensitive fluorescent probes and sensors used in cellular imaging and biochemical detection.
• Metabolic Pathway Research: Used to investigate and model Phase II drug metabolism, specifically glucuronidation, in hepatic and extrahepatic tissues.
• Biomarker Assay Development: Employed in the development of diagnostic kits and assays for detecting specific enzyme activities related to metabolic disorders.
• Pharmaceutical R&D: Utilized in early-stage drug discovery to assess the metabolic fate and potential drug-drug interactions of new chemical entities.
• Academic Research: A valuable tool in university and institutional labs for fundamental studies in biochemistry, enzymology, and chemical biology.

Basic Information

Product Name	1-Pyrenyl -D-Glucopyranosiduronic Acid Methyl Ester
CAS No.	27735-78-0
Molecular Formula	C23H22O8
Molecular Weight	426.42 g/mol
Synonyms	1-Pyrenyl β-D-Glucopyranosiduronic Acid Methyl Ester; Methyl (1-pyrenyl)-β-D-glucopyranosiduronate; Pyrenyl Glucuronide Methyl Ester; 1-Pyrenyl-β-D-glucuronide Methyl Ester; β-D-Glucopyranosiduronic acid, 1-pyrenyl-, methyl ester; Methyl 1-pyrenyl-β-D-glucopyranosiduronate; 1-Pyrenyl β-D-glucuronide methyl ester
EINECS	Contact for details

Quality Control

Every batch of 1-Pyrenyl -D-Glucopyranosiduronic Acid Methyl Ester is manufactured and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency, which is critical for reproducible research results. Our products undergo rigorous quality testing, including HPLC for purity and identity confirmation, to ensure compliance with research-grade standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.