Description

1,2-Bis(Difluoromethoxy)Benzene is a specialized fluorinated aromatic ether compound. This high-value intermediate is critical for synthesizing advanced materials and active pharmaceutical ingredients (APIs) due to its unique difluoromethoxy substituents, which can significantly alter electronic properties and metabolic stability. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and advanced polymer sectors for developing next-generation products.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly where the difluoromethoxy group is used to improve bioavailability and metabolic resistance.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and pesticides with enhanced activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a core structure in the development of fluorinated components for electronic display and lighting technologies.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific properties like chemical resistance, thermal stability, or altered dielectric constant.
• Organic Synthesis Reagent: Employed in research laboratories for introducing difluoromethoxy functionalities into complex organic molecules.
• Fluorinated Surfactant/Additive Precursor: Used in the manufacture of surface-active agents and performance additives for niche industrial applications.

Basic Information

Product Name	1,2-Bis(Difluoromethoxy)Benzene
CAS No.	27691-14-1
Molecular Formula	C8H6F4O2
Molecular Weight	210.13 g/mol
Synonyms	o-Bis(Difluoromethoxy)Benzene; 1,2-Bis(Difluoromethoxy)benzene; Benzene, 1,2-bis(difluoromethoxy)-; 1,2-Difluoromethoxybenzene (ambiguous); o-Difluoromethoxybenzene (ambiguous); 27691-14-1; NSC 406915
EINECS	Contact for details

Quality Control

Our 1,2-Bis(Difluoromethoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	≤ 2.0% (total)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.