Description

Boc-Tranexamic Acid CAS NO 27687-14-5 is a protected derivative of the antifibrinolytic agent tranexamic acid, where the amino group is shielded by a tert-butoxycarbonyl (Boc) protecting group. This modification is critical for enabling selective peptide synthesis and advanced pharmaceutical research, preventing unwanted side reactions during complex molecular assembly. It is an essential building block for medicinal chemists and researchers in the pharmaceutical and biotechnology sectors developing novel hemostatic agents and protease inhibitors.

Application

• Pharmaceutical Intermediate: Key building block in the synthetic pathway of novel tranexamic acid derivatives and peptide-based therapeutics.
• Medicinal Chemistry Research: Used in the design and synthesis of potential drug candidates targeting fibrinolysis, inflammation, and bleeding disorders.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to ensure reaction specificity.
• Bioconjugation: Employed in the development of drug-polymer conjugates or diagnostic agents where a protected amine functionality is required.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.
• Academic & Institutional R&D: Fundamental reagent in university and research institute labs studying hemostasis, protease mechanisms, and organic synthesis methodologies.

Basic Information

Product Name	Boc-Tranexamic Acid
CAS No.	27687-14-5
Molecular Formula	C14H25NO6
Molecular Weight	303.35 g/mol
Synonyms	N-Boc-tranexamic acid; N-(tert-Butoxycarbonyl)-4-(aminomethyl)cyclohexanecarboxylic acid; (trans)-4-[[(1,1-Dimethylethoxy)carbonyl]aminomethyl]cyclohexanecarboxylic Acid; Boc-4-(aminomethyl)cyclohexanecarboxylic acid; Boc-TXA; t-BOC-tranexamic acid; N-Boc-trans-4-(aminomethyl)cyclohexanecarboxylic acid; Tranexamic Acid Boc Ester
EINECS	Contact for details

Quality Control

Our Boc-Tranexamic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide detailed Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.