Description

Quinidine Polygalacturonate CAS NO 27555-34-6 is a pharmaceutical-grade salt formed from the alkaloid quinidine and polygalacturonic acid. This compound is valued for its specific pharmacological activity, primarily as an antiarrhythmic agent, and its formulation properties. It is a critical material for manufacturers in the pharmaceutical industry developing cardiac medications, as well as for research institutions conducting pharmacological studies.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active component in antiarrhythmic drug formulations for treating cardiac conditions like atrial fibrillation and flutter.
• Cardiovascular Research: A standard compound used in preclinical and clinical research to study heart rhythm disorders and the mechanism of Class I antiarrhythmic drugs.
• Reference Standard: Serves as a high-purity chemical reference standard (CRS) for quality control and analytical method development in pharmacopeial testing (e.g., USP, EP).
• Drug Delivery Systems: Utilized in advanced formulation studies, leveraging the polygalacturonate moiety for potential modified-release or targeted delivery applications.
• Biochemical Reagent: Employed in laboratory settings as a reagent to investigate ion channel (particularly sodium channel) function and electrophysiology.

Basic Information

Product Name	Quinidine Polygalacturonate
CAS No.	27555-34-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Quinidine Polygalacturonate; Quinidine Pectinate; Cinchonan-9-ol, 6'-methoxy-, (9S)-, polymer with α-D-galactopyranuronic acid; Quinidine Galacturonate; Quinidine Pectin; Quinidine Polymannuronate (related); Quinidine Alginate (related); Antiarrhythmic Agent Quinidine Salt
EINECS	Contact for details

Quality Control

Our Quinidine Polygalacturonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, suitable for pharmaceutical applications. Certificates of Analysis (COA) documenting compliance with relevant standards are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to standard
Assay (Quinidine Content)	Contact for details
Loss on Drying	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Contact for details
Microbiological Enumeration	Meets Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.