Description

Methyl-n-Boc-4-Benzyloxy-L-Phenyl Alanine CAS NO 27513-44-6 is a protected amino acid derivative, specifically an N-Boc and side-chain benzyl-protected L-phenylalanine analog. This compound is a crucial chiral building block in the synthesis of complex peptides and peptidomimetics, offering high stereochemical purity and stability for demanding coupling reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including enzyme inhibitors and receptor modulators.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Solid-Phase Peptide Synthesis (SPPS): Used as a protected amino acid monomer for the controlled, sequential assembly of custom peptide sequences.
• Medicinal Chemistry Research: Serves as a building block for creating libraries of peptidomimetics and constrained peptides to explore structure-activity relationships (SAR).
• Bioconjugation: Employed in the synthesis of peptide tags, linkers, and carriers for drug delivery systems and diagnostic probes.
• Chemical Biology Probes: Integral to the production of labeled or modified peptides used as tools to study biological pathways and protein functions.

Basic Information

Product Name	Methyl-n-Boc-4-Benzyloxy-L-Phenyl Alanine
CAS No.	27513-44-6
Molecular Formula	C22H27NO5
Molecular Weight	385.46 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-O-benzyl-L-tyrosine methyl ester; Boc-Tyr(Bzl)-OMe; Methyl N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-L-tyrosinate; Boc-O-benzyl-L-tyrosine methyl ester; L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-, methyl ester; (2S)-2-[(tert-Butoxycarbonyl)amino]-3-[4-(benzyloxy)phenyl]propanoic acid methyl ester; Boc-L-Tyr(Bzl)-OMe
EINECS	Contact for details

Quality Control

Our Methyl-n-Boc-4-Benzyloxy-L-Phenyl Alanine is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity, suitable for sensitive pharmaceutical research. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to relevant industry standards for fine chemical manufacturing, and specifications can be aligned with client requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.