Description

2-(2-Bromo-5-Methoxyphenyl)Acetonitrile is a versatile and high-purity brominated aromatic nitrile building block essential for advanced organic synthesis. This compound is critical for the development of complex molecules, offering a reactive site for further functionalization. It is primarily utilized by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with complex aryl-ether or substituted phenyl structures.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents where the bromo-methoxyphenyl moiety is a required pharmacophore.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers due to its aromatic and polarizable nature.
• Custom Synthesis and Contract Manufacturing: A valuable building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-(2-Bromo-5-Methoxyphenyl)Acetonitrile
CAS No.	27387-23-1
Molecular Formula	C9H8BrNO
Molecular Weight	226.07 g/mol
Synonyms	(2-Bromo-5-methoxyphenyl)acetonitrile; 2-Bromo-5-methoxybenzyl cyanide; α-Cyano-2-bromo-5-methoxy toluene; 2-Bromo-5-methoxyphenylacetonitrile; 2-Bromo-5-methoxybenzeneacetonitrile; (2-Bromo-5-methoxyphenyl)ethanenitrile; 27387-23-1
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Bromo-5-Methoxyphenyl)Acetonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee supply reliability and technical compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.