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Metaraminol Enantiomer (25 Mg) (3-[(1S,2R)-2-Amino-1-Hydroxypropyl]Phenol D-Tartrate) CAS NO 27303-40-8


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CAS No.:27303-40-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Metaraminol Enantiomer (25 Mg) (3-[(1S,2R)-2-Amino-1-Hydroxypropyl]Phenol D-Tartrate) is a high-purity, single-isomer form of the potent sympathomimetic amine, metaraminol. This specific enantiomer is critical for pharmaceutical research and development, particularly in studying receptor selectivity and developing safer, more effective cardiovascular agents. It is an essential reference standard and key starting material for researchers and manufacturers in the advanced pharmaceutical and fine chemical sectors. The compound is supplied as a 25 mg unit, ideal for precise analytical and developmental work.

Application

  • Pharmaceutical Reference Standard: Used as a certified standard for quality control and assay validation in drug manufacturing.
  • Cardiovascular Research: Critical for pharmacological studies targeting α- and β-adrenergic receptors to investigate pressor effects and hemodynamics.
  • Active Pharmaceutical Ingredient (API) Intermediate: Serves as a high-purity chiral building block in the synthesis of specialized pharmaceutical formulations.
  • Analytical Method Development: Employed in HPLC, LC-MS, and other chromatographic methods for method development and calibration.
  • Metabolite and Impurity Profiling: Used to identify and quantify related substances and degradation products in stability studies.
  • Academic and Clinical Research: Supports fundamental research into autonomic nervous system function and the mechanisms of vasopressor agents.

Basic Information

Product Name Metaraminol Enantiomer (25 Mg) (3-[(1S,2R)-2-Amino-1-Hydroxypropyl]Phenol D-Tartrate)
CAS No. 27303-40-8
Molecular Formula C9H13NO2 • C4H6O6
Molecular Weight 317.27 g/mol (for the D-tartrate salt)
Synonyms (1S,2R)-Metaraminol D-Tartrate; L-erythro-Metaraminol D-Tartrate; (-)-Metaraminol D-Tartrate; (1S,2R)-3-(2-Amino-1-hydroxypropyl)phenol D-Tartrate; Aramine Enantiomer; Metaraminol Bitartrate Enantiomer; 3-[(1S,2R)-2-Amino-1-hydroxypropyl]phenol (2R,3R)-2,3-dihydroxybutanedioate
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Quality Control

Our Metaraminol Enantiomer is manufactured under strict quality systems to ensure the highest standards of purity and chiral integrity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles. We adhere to relevant ICH guidelines for stability and analytical method validation. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed immediately after use to minimize exposure to air and humidity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0% (on anhydrous basis)
Enantiomeric Purity (Chiral HPLC) ≥ 99.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm
Related Substances (HPLC) Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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