Description

2-[3-(Butyrylamino)-2,4,6-Triiodobenzyl]Butyric Acid is a high-purity, triiodinated organic compound primarily used as a key intermediate in the synthesis of X-ray contrast media. This compound matters because it provides the essential iodine atoms required for effective radiographic imaging, ensuring high opacity and diagnostic clarity. It is critically needed by pharmaceutical manufacturers and fine chemical suppliers serving the medical diagnostics industry, where consistent quality and reliable supply are paramount for regulatory compliance and patient safety.

Application

• Primary Intermediate for X-ray Contrast Agents: Serves as the foundational building block in the synthesis of non-ionic, low-osmolar contrast media like iopamidol and iohexol.
• Pharmaceutical Research & Development: Used in the discovery and development of new iodinated contrast agents with improved safety and efficacy profiles.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for specialized diagnostic compounds.
• Radiology & Diagnostic Imaging: Indirectly essential for producing agents used in computed tomography (CT), angiography, and urography.
• GMP Manufacturing: Supplied as a critical raw material under controlled conditions for the production of finished drug substances (APIs).

Basic Information

Product Name	2-[3-(Butyrylamino)-2,4,6-Triiodobenzyl]Butyric Acid
CAS No.	27293-82-9
Molecular Formula	C15H19I3N2O3
Molecular Weight	647.04 g/mol
Synonyms	Butyric acid, 2-[3-(butyrylamino)-2,4,6-triiodobenzyl]-; 3-Butyrylamino-2,4,6-triiodohydrocinnamic acid; 5-Acetamido-2,4,6-triiodo-N-methylisophthalamic acid derivative (precursor); Iopamidol intermediate; Iohexol intermediate; Triiodobenzylbutyric acid derivative; N-Butyryl-3-amino-2,4,6-triiodohydrocinnamic acid
EINECS	Contact for details

Quality Control

Our 2-[3-(Butyrylamino)-2,4,6-Triiodobenzyl]Butyric Acid is manufactured under strict quality systems to meet the exacting standards of the pharmaceutical industry. Production adheres to current Good Manufacturing Practices (cGMP) where required. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with ICH Q7 guidelines and relevant pharmacopeial standards for intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen) when not in use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Iodine Content	57.0 - 59.0 %
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.