Description

Methyl 3,3,3-Trifluoroalaninate is a high-purity fluorinated amino acid ester, a key building block in advanced organic synthesis. This compound is valued for its trifluoromethyl group, which imparts unique electronic and steric properties critical for modifying the biological activity and metabolic stability of target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of fluorinated peptides, protease inhibitors, and other bioactive molecules where the CF₃ group enhances lipophilicity and metabolic resistance.
• Agrochemical Synthesis: Used in developing advanced herbicides, fungicides, and pesticides, leveraging the fluorine atoms to improve efficacy and environmental profile.
• Material Science Research: Serves as a monomer or modifier for creating specialty polymers and coatings with tailored surface properties and chemical resistance.
• Fluorine Chemistry & Methodology Development: An essential reagent for academic and industrial research focused on new fluorination techniques and C–F bond formation reactions.
• Ligand and Catalyst Design: Incorporated into chiral ligands and organocatalysts to influence stereoselectivity in asymmetric synthesis.
• Diagnostic Agent Development: Potential use in synthesizing fluorinated probes and contrast agents for imaging applications.

Basic Information

Product Name	Methyl 3,3,3-Trifluoroalaninate
CAS No.	27240-44-4
Molecular Formula	C₄H₆F₃NO₂
Molecular Weight	157.09 g/mol
Synonyms	Methyl 2-amino-3,3,3-trifluoropropanoate; 3,3,3-Trifluoroalanine methyl ester; Alanine, 3,3,3-trifluoro-, methyl ester; Methyl 3,3,3-trifluoro-2-aminopropanoate; 2-Amino-3,3,3-trifluoropropionic acid methyl ester; (RS)-Methyl 3,3,3-trifluoroalaninate; DL-3,3,3-Trifluoroalanine methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3,3,3-Trifluoroalaninate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GLP and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.