Description

Thiazole, 2-Fluoro-5-Methyl- is a high-purity fluorinated heterocyclic building block, essential for advanced organic synthesis. This compound is valued for its role in introducing the thiazole scaffold with specific fluorine substitution, which is critical for modulating the biological activity and physicochemical properties of target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antiviral agents, and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized ligands in catalysis or for creating novel fluorinated polymers with specialized properties.
• Chemical Biology Probes: Employed in the synthesis of fluorescent tags or molecular probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Thiazole, 2-Fluoro-5-Methyl-
CAS No.	27225-15-6
Molecular Formula	C4H4FNS
Molecular Weight	117.14 g/mol
Synonyms	2-Fluoro-5-methylthiazole; 5-Methyl-2-fluorothiazole; 2-Fluoro-5-methyl-1,3-thiazole; Fluoromethylthiazole; 27225-15-6; Thiazole, 2-fluoro-5-methyl-; 2-Fluor-5-methylthiazol
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-Methylthiazole is produced and analyzed under strict quality management protocols to ensure consistency and reliability for sensitive synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and potential concentration changes.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.