Description

2-(3,4-Dihydroxyphenyl)Ethyl-2,2-D2-Amine Hcl is a deuterated derivative of dopamine, a critical catecholamine neurotransmitter. This compound is specifically designed for research and development applications where isotopic labeling is required for advanced analytical studies, such as mass spectrometry and metabolic pathway tracing. It is essential for pharmaceutical R&D, analytical chemistry, and biochemical research focused on neurological processes and drug metabolism.

Application

• Pharmaceutical Research & Development: Used as a deuterium-labeled internal standard for the precise quantification of dopamine and related metabolites in biological matrices via LC-MS/MS and GC-MS.
• Metabolic Pathway Studies: Enables the tracing of dopamine uptake, synthesis, and degradation pathways in neurological and pharmacological research.
• Analytical Chemistry: Serves as a high-purity reference standard for calibrating analytical instruments and validating methods in quality control laboratories.
• Neurochemical Research: A key tool for investigating the role of dopamine in the central nervous system, including studies on Parkinson's disease, addiction, and psychiatric disorders.
• Isotope Dilution Mass Spectrometry (IDMS): Critical for achieving high accuracy and precision in quantitative bioanalysis due to its stable isotopic signature.
• Precursor for Labeled Compounds: Can be used in the synthesis of other deuterium-labeled bioactive molecules or pharmaceutical intermediates.

Basic Information

Product Name	2-(3,4-Dihydroxyphenyl)Ethyl-2,2-D2-Amine Hcl
CAS No.	27160-01-6
Molecular Formula	C8H9D2ClNO2
Molecular Weight	189.66 g/mol
Synonyms	Dopamine-2,2-d2 Hydrochloride; 2-(3,4-Dihydroxyphenyl)ethyl-2,2-d2-amine hydrochloride; 4-(2-Aminoethyl)-1,2-benzenediol-2,2-d2 hydrochloride; 3,4-Dihydroxyphenethylamine-2,2-d2 HCl; 3-Hydroxytyramine-2,2-d2 hydrochloride; DA-d2 HCl; Deuterated Dopamine HCl; 2,2-Dideuterodopamine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(3,4-Dihydroxyphenyl)Ethyl-2,2-D2-Amine Hcl is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and isotopic enrichment. Certificates of Analysis (COA) detailing purity, isotopic purity (D-content), and impurity profiles are provided to guarantee reliability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.