Description

Z-D-Glu(Ome)-Oh is a protected amino acid derivative, specifically the Z-protected D-glutamic acid 5-methyl ester. This compound is a crucial chiral building block in the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, diagnostic tools, and advanced biochemical research.

Application

• Pharmaceutical Intermediates: Serves as a key chiral synthon in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) for introducing D-glutamic acid residues with orthogonal side-chain protection.
• Biochemical Research: Employed in studying enzyme-substrate interactions, receptor binding, and the structure-activity relationships (SAR) of peptides.
• Proteomics & Diagnostics: Acts as a component in the preparation of specialized peptides for use as standards, probes, or diagnostic markers.
• Material Science: Potential use in the development of bio-conjugates and functionalized polymers for specialized applications.

Basic Information

Product Name	Z-D-Glu(Ome)-Oh
CAS No.	27025-24-7
Molecular Formula	C14H17NO6
Molecular Weight	295.29 g/mol
Synonyms	N-Carbobenzoxy-D-glutamic acid 5-methyl ester; Z-D-Glu-OMe; (R)-2-((((Benzyloxy)carbonyl)amino)pentanedioic acid 5-methyl ester; D-Glutamic acid, N-[(phenylmethoxy)carbonyl]-, 5-methyl ester; N-Cbz-D-glutamic acid γ-methyl ester; Z-D-Glu(OMe)-OH; Benzyloxycarbonyl-D-glutamic acid 1-methyl ester; CBZ-D-Glutamic Acid 5-Methyl Ester
EINECS	Contact for details

Quality Control

Our Z-D-Glu(Ome)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.