Description

Carbobenzoxy-D,L-Tryptophanamide is a protected derivative of the amino acid tryptophan, widely utilized as a key synthetic intermediate in peptide chemistry. Its primary value lies in providing a versatile building block for the controlled synthesis of complex peptides and peptidomimetics, where the carbobenzoxy (Cbz) group offers orthogonal protection. This compound is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers engaged in the creation of novel therapeutic agents, bioactive peptides, and advanced materials.

Application

• Peptide Synthesis Intermediate: A fundamental building block for the solid-phase and solution-phase synthesis of peptides containing tryptophan residues.
• Pharmaceutical Research & Development: Used in the discovery and development of peptide-based drugs, hormone analogs, and enzyme inhibitors.
• Bioconjugation & Probe Development: Serves as a precursor for creating fluorescent probes, affinity labels, or other modified peptides for biochemical studies.
• Academic & Industrial Research: Employed in chemical biology and medicinal chemistry research to study protein-protein interactions and design new bioactive compounds.
• Production of Protected Amino Acid Derivatives: Used for further chemical modifications to create specialized, non-natural amino acid analogs.
• Combinatorial Chemistry Libraries: A valuable reagent for generating diverse libraries of compounds for high-throughput screening in drug discovery.

Basic Information

Item	Details
Product Name	Carbobenzoxy-D,L-Tryptophanamide
CAS No.	27018-75-3
Molecular Formula	C20H21N3O3
Molecular Weight	351.40 g/mol
Synonyms	N-Carbobenzoxy-DL-tryptophanamide; Cbz-DL-Trp-NH2; Z-DL-Trp-NH2; Nα-Carbobenzoxy-DL-tryptophanamide; Benzyl N-[(1RS)-1-(aminocarbonyl)-2-(1H-indol-3-yl)ethyl]carbamate; (RS)-2-[(Benzyloxy)carbonyl]amino]-3-(1H-indol-3-yl)propanamide; DL-Tryptophan, N-[(phenylmethoxy)carbonyl]-, amide
EINECS	Contact for details

Quality Control

Our Carbobenzoxy-D,L-Tryptophanamide is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR). A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details (racemic mixture)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.