Description

2-Phenylindole-3-Acetonitrile is a versatile indole-based organic intermediate of significant importance in advanced chemical synthesis. Its unique molecular structure, featuring both phenyl and nitrile functional groups on the indole core, makes it a valuable precursor for the development of complex heterocyclic compounds. This high-purity building block is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for applications in drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and oncological pathways.
• Agrochemical Synthesis: Serves as a precursor in the creation of advanced herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Organic Light-Emitting Diode (OLED) Materials: Used in the synthesis of electron-transport or host materials for OLED displays and lighting due to its rigid, conjugated structure.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing specialized indole-based dyes and high-performance pigments.
• Academic and Industrial Research: A valuable compound for methodological studies in organic chemistry, including novel cyclization and functionalization reactions.
• Ligand and Catalyst Development: Utilized in the preparation of nitrogen-containing ligands for coordination chemistry and catalytic applications.

Basic Information

Product Name	2-Phenylindole-3-Acetonitrile
CAS No.	27005-52-3
Molecular Formula	C₁₆H₁₂N₂
Molecular Weight	232.28 g/mol
Synonyms	2-Phenyl-1H-indole-3-acetonitrile; 3-(Cyanomethyl)-2-phenyl-1H-indole; 2-Phenylindol-3-ylacetonitrile; (2-Phenyl-1H-indol-3-yl)acetonitrile; α-Cyano-2-phenylindole-3-methyl; 2-Phenyl-3-indoleacetonitrile; 27005-52-3; NSC 163022
EINECS	Contact for details

Quality Control

Our 2-Phenylindole-3-Acetonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.