Description

n-(2,5-Dimethoxyphenyl)-2-Iodoacetamide is a specialized halogenated acetamide derivative, a key building block in advanced organic synthesis. Its molecular structure, featuring both an iodoacetamide group and dimethoxyphenyl moiety, makes it a valuable reagent for introducing specific functional handles into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological and oncological pathways.
• Bioconjugation Reagent: Used in biochemical research to modify proteins, peptides, or antibodies via alkylation of thiol groups, enabling the study of protein function or the creation of antibody-drug conjugates (ADCs).
• Agrochemical Research: Employed in the development of new herbicides, fungicides, or plant growth regulators where the dimethoxyphenyl group is a common pharmacophore.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probe: Utilized to create activity-based probes for studying enzyme mechanisms and identifying drug targets within complex biological systems.
• Organic Synthesis Building Block: Facilitates C-C and C-N bond-forming reactions, such as cross-coupling reactions, due to the reactivity of the iodine atom.

Basic Information

Product Name	n-(2,5-Dimethoxyphenyl)-2-Iodoacetamide
CAS No.	26958-85-0
Molecular Formula	C10H12INO3
Molecular Weight	321.11 g/mol
Synonyms	2-Iodo-N-(2,5-dimethoxyphenyl)acetamide; N-(2,5-Dimethoxyphenyl)-2-iodoacetamide; 2-Iodoacet-2',5'-dimethoxyanilide; Acetamide, 2-iodo-N-(2,5-dimethoxyphenyl)-; Iodoacetamide, N-(2,5-dimethoxyphenyl)-; 26958-85-0; 2-Iodo-N-(2,5-dimethoxy-phenyl)acetamide
EINECS	Contact for details

Quality Control

Every batch of n-(2,5-Dimethoxyphenyl)-2-Iodoacetamide is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be performed under subdued lighting or using amber glass containers to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.