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[6R-[6Alpha,7Beta(S*)]]-3-(Acetoxymethyl)-7-(5-Amino-5-Carboxyvalerylamino)-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid, Potassium Salt CAS NO 26944-38-7


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CAS No.:26944-38-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

[6R-[6Alpha,7Beta(S*)]]-3-(Acetoxymethyl)-7-(5-Amino-5-Carboxyvalerylamino)-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid, Potassium Salt is a high-purity potassium salt derivative of a cephalosporin nucleus, serving as a critical advanced pharmaceutical intermediate. Its value lies in enabling the synthesis of specific, potent cephalosporin antibiotics, offering manufacturers precise control over the final API's structure and activity. This compound is essential for pharmaceutical R&D laboratories and bulk drug manufacturers focused on developing and producing next-generation antibiotic therapies.

Application

  • Active Pharmaceutical Ingredient (API) Synthesis: Key intermediate in the production of specific semi-synthetic cephalosporin antibiotics.
  • Pharmaceutical Research & Development: Used in medicinal chemistry for designing and testing novel antibiotic candidates with improved efficacy.
  • Process Chemistry & Scale-Up: Serves as a defined starting material for optimizing and scaling manufacturing routes for cephalosporin drugs.
  • Reference Standard: Can be utilized as a high-purity analytical standard for quality control and regulatory submissions.
  • Custom Synthesis: Basis for the preparation of tailored cephalosporin derivatives for specialized therapeutic applications.

Basic Information

Product Name [6R-[6Alpha,7Beta(S*)]]-3-(Acetoxymethyl)-7-(5-Amino-5-Carboxyvalerylamino)-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid, Potassium Salt
CAS No. 26944-38-7
Molecular Formula C17H22KN3O8S
Molecular Weight 467.54 g/mol
Synonyms 7-ACA Potassium Salt Derivative; 7β-[(5-Amino-5-carboxypentanoyl)amino]-3-(acetoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Potassium Salt; Potassium (6R,7R)-7-[(R)-2-Amino-2-carboxyethylthioacetamido]-3-acetoxymethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Cephalosporin C Nucleus Potassium Salt; GL-7-ACA Potassium Salt; 7-ADCA Precursor Potassium Salt; Antibiotic Intermediate Potassium Salt.
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Quality Control

Our [6R-[6Alpha,7Beta(S*)]]-3-(Acetoxymethyl)-7-(5-Amino-5-Carboxyvalerylamino)-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid, Potassium Salt is manufactured under strict quality systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and related substances, to ensure it meets exacting standards suitable for pharmaceutical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Potassium Content Conforms to theoretical
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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