Description

Cyclohexanecarboxylic Acid, 2-Amino-, Hydrazide, (1R,2R)-(-)- (8Ci) is a high-purity, chiral organic compound that serves as a critical building block in advanced chemical synthesis. Its value lies in its dual functional groups—amino and hydrazide—anchored to a stereochemically defined cyclohexane backbone, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require enantiomerically pure intermediates for developing active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators where specific stereochemistry is crucial for bioactivity.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands used in asymmetric hydrogenation and other catalytic processes.
• Peptidomimetic Research: The hydrazide moiety makes it valuable for constructing peptide analogs and constrained scaffolds in medicinal chemistry.
• Fine Chemical Manufacturing: Employed in the custom synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 2-Amino-, Hydrazide, (1R,2R)-(-)- (8Ci)
CAS No.	26685-86-9
Molecular Formula	C7H15N3O
Molecular Weight	157.22 g/mol
Synonyms	(1R,2R)-2-Aminocyclohexanecarboxylic Acid Hydrazide; (-)-cis-2-Aminocyclohexanecarboxylic Acid Hydrazide; (1R,2R)-(-)-2-Amino-1-cyclohexanecarboxylic Acid Hydrazide; L-2-Aminocyclohexanecarboxylic Acid Hydrazide (cis-); cis-2-ACHC Hydrazide; (1R,2R)-2-ACHC Hydrazide; Chiral Cyclohexane Amino Acid Hydrazide
EINECS	Contact for details

Quality Control

Our production of Cyclohexanecarboxylic Acid, 2-Amino-, Hydrazide, (1R,2R)-(-)- (8Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. We employ advanced analytical techniques, including chiral HPLC and NMR, to verify identity and purity. Certificates of Analysis (COA) detailing specific results for chiral purity, assay, and impurities are provided with every shipment. Our quality management system supports compliance with cGMP and ISO standards for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider keeping the container under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1R,2R)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.