Description

H-Dl-Arg(Tos)-Oh CAS NO 26647-58-5 is a protected derivative of the amino acid arginine, featuring a tosyl (Tos) group on the guanidine side chain. This modification is critical for peptide synthesis, as it prevents unwanted side reactions and allows for selective deprotection, ensuring high-purity final products. It is an essential building block for researchers and manufacturers in pharmaceutical development, biochemical research, and the production of specialized peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the controlled assembly of complex peptide chains.
• Pharmaceutical Intermediate: Used in the research and development of novel therapeutic peptides targeting various diseases.
• Biochemical Research: Serves as a crucial reagent for studying protein-protein interactions, enzyme substrates, and signal transduction pathways.
• Peptidomimetic Design: Employed to create stable, bioavailable analogs of natural peptides for drug discovery.
• Custom Peptide Production: A fundamental raw material for CROs and CDMOs offering bespoke peptide manufacturing services.
• Protecting Group Chemistry: Demonstrates the application of tosyl protection in multi-step organic synthesis strategies.

Basic Information

Product Name	H-Dl-Arg(Tos)-Oh
CAS No.	26647-58-5
Molecular Formula	C13H20N4O4S
Molecular Weight	328.39 g/mol
Synonyms	NG-Tosyl-DL-arginine; DL-Arginine, N2-(p-toluenesulfonyl)-; H-Arg(Tos)-OH (racemic); Nω-Tosyl-DL-arginine; p-Toluenesulfonyl-DL-arginine; Tos-DL-Arg-OH; (RS)-2-Amino-5-[(4-methylphenyl)sulfonylamino]pentanoic acid; NG-Tosyl-DL-Arg-OH
EINECS	Contact for details

Quality Control

Our H-Dl-Arg(Tos)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for peptide synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability, consistency, and reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Racemic mixture (DL)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.