Description

Mycophenolic Hydroxy Lactone is a key pharmaceutical intermediate and a derivative of mycophenolic acid. This compound is of significant commercial and research interest due to its role in the synthesis of immunosuppressive agents and other biologically active molecules. It is primarily utilized by manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for the development of new drug candidates and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potent immunosuppressant drugs, including mycophenolate mofetil and mycophenolate sodium.
• Biochemical Research: Used as a reference standard and a starting material in pharmacological and metabolic studies related to immunosuppression.
• Fine Chemical Synthesis: Serves as a versatile precursor for the preparation of various mycophenolic acid analogs and derivatives with potential therapeutic applications.
• API Manufacturing: Employed in the controlled production of Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for medicinal chemistry and drug discovery programs.

Basic Information

Product Name	Mycophenolic Hydroxy Lactone
CAS No.	26644-06-4
Molecular Formula	C17H18O6
Molecular Weight	318.32 g/mol
Synonyms	4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl-4-hexenoic acid δ-lactone; 6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid lactone; Mycophenolic acid lactone; 6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid μ-lactone; (E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid δ-lactone
EINECS	Contact for details

Quality Control

Our Mycophenolic Hydroxy Lactone is produced and tested to meet the stringent requirements of pharmaceutical-grade intermediates. Quality is assured through rigorous in-process and final release testing, which may include HPLC for purity, residual solvent analysis, and identification by spectroscopic methods. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing all specified parameters. We support development and commercial projects with consistent quality and full traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.