Description

3,3'-Thiobis(n-Trifluoroacetyl-L-Alanine)Dimethyl Ester is a specialized chiral building block and derivatization agent used in advanced organic synthesis. This compound is valued for its role in the preparation of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is essential for researchers and manufacturers in the life sciences and specialty chemical sectors who require high-purity intermediates for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in the synthesis and modification of peptides, serving as a protecting group or a structural component.
• Asymmetric Synthesis: Employed as a chiral auxiliary or reagent in stereoselective reactions to create enantiomerically pure compounds.
• Derivatization Agent: Facilitates the analysis and purification of complex mixtures in analytical chemistry and process development.
• Bioconjugation: Useful in creating chemical linkages for bioconjugates used in drug delivery and diagnostic applications.
• Material Science Research: Investigated for the development of novel polymers and advanced materials with specific chiral properties.

Basic Information

Product Name	3,3'-Thiobis(n-Trifluoroacetyl-L-Alanine)Dimethyl Ester
CAS No.	26527-25-3
Molecular Formula	C₁₄H₁₆F₆N₂O₆S
Molecular Weight	454.34 g/mol
Synonyms	Bis(N-trifluoroacetyl-L-alanine) Disulfide Dimethyl Ester; L-Alanine, N-[3-[[(1S)-1-(methoxycarbonyl)-2,2,2-trifluoroethyl]amino]-3-thioxopropyl]-2,2,2-trifluoro-, methyl ester; 3,3'-Dithiobis[N-(trifluoroacetyl)-L-alanine] Dimethyl Ester; (S,S)-3,3'-Thiobis(2,2,2-trifluoro-N-(1-methoxy-1-oxopropan-2-yl)acetamide); NTFAL Disulfide Dimethyl Ester
EINECS	Contact for details

Quality Control

Our 3,3'-Thiobis(n-Trifluoroacetyl-L-Alanine)Dimethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.