Description

L-β-Homophenylalanine, Hplc 98% is a high-purity, non-proteinogenic amino acid derivative characterized by its homophenylalanine backbone with a β-carbon linkage. This specific chiral building block is critical for synthesizing complex molecules where precise stereochemistry and structural integrity are paramount. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of peptide-based therapeutics, enzyme inhibitors, and advanced chiral intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of peptide drugs, protease inhibitors, and other bioactive compounds.
• Peptide Synthesis: Serves as a specialized amino acid residue in solid-phase and solution-phase peptide synthesis for creating novel peptide sequences.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and for probing structure-activity relationships (SAR) in medicinal chemistry.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to construct complex chiral molecules.
• Reference Standard: Functions as a high-purity analytical standard for quality control and method development in HPLC and LC-MS analysis.

Basic Information

Product Name	L-β-Homophenylalanine, Hplc 98%
CAS No.	26250-87-3
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	(S)-2-Amino-4-phenylbutanoic acid; L-2-Amino-4-phenylbutyric acid; Hph; L-Homo-Phe; L-β-Homophenylalanine; (S)-β-Homophenylalanine; L-4-Phenyl-2-aminobutanoic acid; BRN 2208243
EINECS	Contact for details

Quality Control

Every batch of our L-β-Homophenylalanine is produced and tested under strict quality management protocols to ensure it meets the high standards required for pharmaceutical research and synthesis. The HPLC 98% purity grade is verified using validated analytical methods, including chiral HPLC to confirm enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Contact for details
Chiral Purity (HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.