Description

2-o-(p-Nitrophenyl)-α-D-n-Acetylneuraminic Acid is a specialized, high-purity biochemical derivative of sialic acid, a critical carbohydrate moiety in glycobiology. This compound matters as a key intermediate and research tool for studying sialidase (neuraminidase) enzyme activity and carbohydrate-protein interactions. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing diagnostic assays, antiviral agents, and novel glycoconjugate therapeutics.

Application

• Enzyme Substrate for Neuraminidase/Sialidase Assays: Used as a chromogenic substrate in enzymatic activity tests for influenza virus research and other sialidase-producing pathogens.
• Biochemical Research Reagent: Serves as a critical intermediate in the synthesis of more complex sialic acid derivatives and glycoconjugates for structural and functional studies.
• Pharmaceutical Intermediate: Employed in the research and development stages of novel antiviral drugs and inhibitors targeting viral neuraminidases.
• Diagnostic Kit Development: A key component in the formulation of diagnostic kits for detecting and quantifying sialidase enzyme activity in clinical and research samples.
• Glycobiology Studies: Utilized to investigate the role of sialic acids in cell signaling, immune response, and pathogen recognition.

Basic Information

Product Name	2-o-(p-Nitrophenyl)-α-D-n-Acetylneuraminic Acid
CAS No.	26112-88-9
Molecular Formula	C17H22N2O11
Molecular Weight	430.37 g/mol
Synonyms	p-Nitrophenyl-N-acetyl-α-D-neuraminide; 4-Nitrophenyl 5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-non-2-ulopyranosidonic acid; 2-O-(4-Nitrophenyl)-α-D-N-acetylneuraminic acid; Neu5Acα2-O-pNP; p-Nitrophenyl-α-N-acetylneuraminoside; α-Neu5Ac-pNP; Sialic Acid Derivative (pNP)
EINECS	Contact for details

Quality Control

Our 2-o-(p-Nitrophenyl)-α-D-n-Acetylneuraminic Acid is manufactured under strict quality systems suitable for research and development applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure consistent performance and reliability. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.