Description

3-[6-[[3-Carboxy-2,4,6-Triiodo-5-[(2-Oxopyrrolidin-1-Yl)Methyl]Phenyl]Carbamoyl]Hexanoylamino]-2,4,6-Triiodo-5-[(2-Oxopyrrolidin-1-Yl)Methyl]Benzoic Acid is a high-purity, iodinated organic compound designed for advanced pharmaceutical and diagnostic applications. Its complex molecular structure, featuring multiple iodine atoms and pyrrolidinone moieties, makes it a critical intermediate for developing X-ray contrast media. This compound is essential for manufacturers and research institutions focused on creating next-generation, non-ionic contrast agents with improved safety and imaging profiles.

Application

• Pharmaceutical Intermediate: Primary building block for the synthesis of non-ionic, monomeric X-ray contrast agents such as Iopromide and Ioversol.
• Diagnostic Imaging Research: Key precursor in R&D for novel iodinated contrast media with enhanced osmolality and vascular tolerance.
• Chemical Synthesis: Used in specialized organic synthesis to introduce high iodine content into target molecules for medical imaging.
• Radiology Product Development: Serves as a critical raw material for companies developing CT (Computed Tomography) and angiography contrast solutions.
• Quality Control Reference Standard: High-purity grade can be utilized as a reference standard for analytical method development and impurity profiling in contrast agent production.

Basic Information

Product Name	3-[6-[[3-Carboxy-2,4,6-Triiodo-5-[(2-Oxopyrrolidin-1-Yl)Methyl]Phenyl]Carbamoyl]Hexanoylamino]-2,4,6-Triiodo-5-[(2-Oxopyrrolidin-1-Yl)Methyl]Benzoic Acid
CAS No.	26090-52-8
Molecular Formula	C31H28I6N4O8
Molecular Weight	1378.00 g/mol
Synonyms	Iopromide Intermediate; Ioversol Intermediate; 5-[Acetyl(2,3-dihydroxypropyl)amino]-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide precursor; 1,3-Bis(1,3-dihydroxy-2-propyl)-5-[N-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodoisophthalamide related compound; 3-Carboxy-2,4,6-triiodo-5-[(2-oxo-1-pyrrolidinyl)methyl]benzoic acid derivative; Non-ionic contrast agent intermediate; Iodinated benzoic acid dimer.
EINECS	Contact for details

Quality Control

Our production of this high-value pharmaceutical intermediate adheres to strict cGMP (current Good Manufacturing Practice) guidelines to ensure batch-to-batch consistency and traceability. Quality is verified through a comprehensive suite of analytical methods including HPLC for purity and impurity profiling, residual solvent analysis, and elemental analysis for iodine content. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Iodine Content	54.0% - 56.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.