Description

4-Hydroxythiobenzamide is a versatile sulfur-containing aromatic compound that serves as a key synthetic intermediate and building block in advanced organic chemistry. Its unique structure, featuring both hydroxyl and thioamide functional groups, makes it valuable for constructing complex molecules with specific electronic and binding properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where the thioamide moiety can act as a bioisostere or metal-chelating group.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides, leveraging its aromatic core for stability and bioactivity.
• Ligand in Coordination Chemistry: Acts as a chelating ligand for transition metals in catalysis and material science, useful for creating metal-organic frameworks (MOFs) or homogeneous catalysts.
• Organic Synthesis Building Block: Employed in heterocyclic chemistry for the construction of sulfur and nitrogen-containing rings, such as thiazoles and benzothiazines.
• Chemical Research Reagent: Utilized in academic and industrial laboratories for methodological studies, asymmetric synthesis, and the development of new synthetic pathways.
• Material Science Precursor: Investigated for the development of organic semiconductors, conductive polymers, or nonlinear optical materials due to its electron-donating and accepting capabilities.

Basic Information

Product Name	4-Hydroxythiobenzamide
CAS No.	25984-63-8
Molecular Formula	C7H7NOS
Molecular Weight	153.20 g/mol
Synonyms	p-Hydroxythiobenzamide; 4-Hydroxybenzenecarbothioamide; Thiobenzamide, 4-hydroxy-; 4-Hydroxybenzothioamide; p-Hydroxybenzothioamide; Benzenecarbothioamide, 4-hydroxy-; 4-Hydroxy-thiobenzamide; 4-Hydroxybenzene-1-carbothioamide
EINECS	Contact for details

Quality Control

Our 4-Hydroxythiobenzamide is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, purity, and impurity profiles. While typically supplied as a research-grade material, production can be aligned with cGMP guidelines for advanced projects requiring stringent documentation and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.