Description

2-Amino-6-(1,2,3-Trihydroxypropyl)-5,6,7,8-Tetrahydro-1H-Pteridin-4-One is a high-purity, advanced pharmaceutical intermediate and biochemical building block. This compound is critical for research and development in life sciences, particularly in the synthesis of complex biomolecules and enzyme cofactors. It is essential for pharmaceutical manufacturers, biotechnology R&D labs, and academic institutions focused on metabolic studies and novel therapeutic development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of specialized folate analogs and other bioactive pteridine derivatives.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to folate metabolism and one-carbon transfer pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Nutraceutical Development: Investigated for potential applications in the development of advanced nutritional supplements and fortified products.
• Academic & Contract Research: Fundamental building block for synthetic organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	2-Amino-6-(1,2,3-Trihydroxypropyl)-5,6,7,8-Tetrahydro-1H-Pteridin-4-One
CAS No.	25976-00-5
Molecular Formula	C9H15N5O4
Molecular Weight	257.25 g/mol
Synonyms	6-(1,2,3-Trihydroxypropyl)-5,6,7,8-tetrahydropterin; 6-(D-erythro-1,2,3-Trihydroxypropyl)-5,6,7,8-tetrahydropterin; 6-Biopterin (reduced form); L-erythro-5,6,7,8-Tetrahydrobiopterin (BH4) related analog; Tetrahydrobiopterin intermediate; Sapropterin precursor; 2-Amino-6-(1,2,3-trihydroxypropyl)-5,6,7,8-tetrahydro-4(1H)-pteridinone
EINECS	Contact for details

Quality Control

Our 2-Amino-6-(1,2,3-Trihydroxypropyl)-5,6,7,8-Tetrahydro-1H-Pteridin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and pharmaceutical use. Certificates of Analysis (COA) with complete traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.