Description

8-Chloro-10-[3-(Methylamino)Propyl]-2-Methoxy-10H-Phenothiazin-3-Ol is a high-purity phenothiazine derivative, a critical intermediate in advanced pharmaceutical synthesis. This compound matters for its role as a key building block in the development of active pharmaceutical ingredients (APIs), particularly in the central nervous system therapeutic class. It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the synthesis of novel drug candidates and reference standards.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of antipsychotic and neuroleptic drug candidates.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural moiety for developing new phenothiazine-based therapeutics.
• Biochemical Research: Used in pharmacological studies to investigate receptor binding and neurological pathways.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for specialized chemical entities.

Basic Information

Product Name	8-Chloro-10-[3-(Methylamino)Propyl]-2-Methoxy-10H-Phenothiazin-3-Ol
CAS No.	25946-86-5
Molecular Formula	C17H19ClN2O2S
Molecular Weight	350.86 g/mol
Synonyms	8-Chloro-10-(3-methylaminopropyl)-2-methoxyphenothiazin-3-ol; 2-Methoxy-8-chloro-10-(3-methylaminopropyl)phenothiazin-3-ol; 25946-86-5; 8-Chloro-2-methoxy-10-(3-methylaminopropyl)phenothiazin-3-ol; 10H-Phenothiazin-3-ol, 8-chloro-10-[3-(methylamino)propyl]-2-methoxy-; 8-Chloro-10-(3-methylaminopropyl)-2-methoxy-10H-phenothiazin-3-ol
EINECS	Contact for details

Quality Control

Our 8-Chloro-10-[3-(Methylamino)Propyl]-2-Methoxy-10H-Phenothiazin-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.