Description

3-Amino-N-(tert-Butyl)Benzamide is a specialized aromatic amide derivative featuring both a primary amine and a sterically hindered tert-butylamide group. This unique bifunctional structure makes it a valuable high-purity building block in advanced organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors seeking to introduce specific steric and electronic properties into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of drug candidates, especially those targeting central nervous system (CNS) disorders, due to its amine functionality and bulky amide group.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, and insecticides where the tert-butyl group can enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Used in organometallic chemistry to create novel ligands for asymmetric catalysis, leveraging the coordinating ability of the amine nitrogen.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for specialty polymers, imparting thermal stability and specific interactive sites.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies in amide coupling reactions and the synthesis of complex heterocycles.
• Material Science: Potential use in the synthesis of organic semiconductors or advanced coatings where its aromatic and amide structure contributes to material properties.

Basic Information

Product Name	3-Amino-N-(tert-Butyl)Benzamide
CAS No.	25900-62-3
Molecular Formula	C11H16N2O
Molecular Weight	192.26 g/mol
Synonyms	3-Amino-N-tert-butylbenzamide; N-(tert-Butyl)-3-aminobenzamide; 3-Aminobenzoic acid tert-butylamide; Benzoic acid, 3-amino-, 1,1-dimethylethylamide; 1,1-Dimethylethyl 3-aminobenzamide; 3-Amino-N-(1,1-dimethylethyl)benzamide; 3-Aminobenzamide, N-tert-butyl-; tert-Butyl 3-aminobenzamide
EINECS	Contact for details

Quality Control

Our 3-Amino-N-(tert-Butyl)Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, prolonged storage under an inert atmosphere (nitrogen or argon) is recommended for optimal long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.