Description

4-Methoxy-2-Nitro-1-(Trifluoromethyl)Benzene is a specialized aromatic compound featuring a unique trifluoromethyl and nitro substitution pattern. This structure makes it a valuable and versatile building block in advanced organic synthesis, particularly for the development of complex molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients. Its distinct electronic properties are leveraged in material science applications as well.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially those requiring the trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Intermediate: Used in the research and production of advanced pesticides and herbicides, where the nitro and trifluoromethyl groups contribute to biological activity.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Dye and Pigment Synthesis: Acts as an intermediate in the manufacture of complex, high-performance dyes and pigments.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic aromatic substitutions, and other transformations to introduce functionalized aryl groups.

Basic Information

Product Name	4-Methoxy-2-Nitro-1-(Trifluoromethyl)Benzene
CAS No.	25889-37-6
Molecular Formula	C8H6F3NO3
Molecular Weight	221.14 g/mol
Synonyms	2-Nitro-4-methoxybenzotrifluoride; 4-Methoxy-2-nitrobenzotrifluoride; 1-Methoxy-2-nitro-4-(trifluoromethyl)benzene; α,α,α-Trifluoro-4-methoxy-2-nitrotoluene; 4-Methoxy-2-nitro-α,α,α-trifluorotoluene; 2-Nitro-4-(trifluoromethyl)anisole; 25889-37-6
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2-Nitro-1-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.