Description

(3-Hydroxyazetidin-1-Yl)(Phenyl)Methanone is a versatile heterocyclic building block featuring both an azetidine ring and a benzophenone moiety. This compound is of significant interest in advanced organic synthesis, particularly for the development of novel pharmacologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Medicinal Chemistry Research: Used as a scaffold for constructing compound libraries via parallel synthesis to explore structure-activity relationships (SAR).
• Protease Inhibitor Development: The azetidine-3-ol structure is a valuable motif in the design of inhibitors for various enzymes, including kinases and proteases.
• Ligand and Catalyst Synthesis: Employed in the preparation of chiral ligands for asymmetric catalysis or as a component in metal-organic frameworks (MOFs).
• Agrochemical Research: Investigated as an intermediate for developing new active ingredients in crop protection products.
• Academic Research: Used in universities and institutes for studying heterocyclic chemistry, reaction mechanisms, and novel synthetic methodologies.

Basic Information

Product Name	(3-Hydroxyazetidin-1-Yl)(Phenyl)Methanone
CAS No.	25566-00-1
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	1-Benzoyl-3-hydroxyazetidine; 3-Hydroxy-1-benzoylazetidine; (3-Hydroxy-1-azetidinyl)(phenyl)methanone; Phenyl(3-hydroxyazetidin-1-yl)methanone; Azetidin-3-ol, 1-benzoyl-; 25566-00-1; (3-Hydroxyazetidin-1-yl)(phenyl)methanone
EINECS	Contact for details

Quality Control

Our (3-Hydroxyazetidin-1-Yl)(Phenyl)Methanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.