Description

4-(3-Trifluoromethylbenzoyl)-Piperidine, Hydrochloride is a high-purity, non-racemic pharmaceutical intermediate and building block. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery. It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers developing novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex piperidine and benzoyl-containing derivatives.
• API Development: Employed in the research and development stages of novel Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: May be used as a tool compound or ligand in biochemical assays and receptor studies.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis projects.

Basic Information

Product Name	4-(3-Trifluoromethylbenzoyl)-Piperidine, Hydrochloride
CAS No.	25519-83-9
Molecular Formula	C13H14F3NO • HCl
Molecular Weight	293.71 g/mol
Synonyms	4-(3-(Trifluoromethyl)benzoyl)piperidine hydrochloride; 1-[3-(Trifluoromethyl)benzoyl]piperidin-4-one hydrochloride (incorrect but common); 4-(α,α,α-Trifluoro-m-toluoyl)piperidine hydrochloride; Piperidine, 4-(3-(trifluoromethyl)benzoyl)-, hydrochloride; 4-(3-Trifluoromethyl-benzoyl)-piperidine HCl; 4-(m-Trifluoromethylbenzoyl)piperidine HCl; 25519-83-9
EINECS	Contact for details

Quality Control

Our 4-(3-Trifluoromethylbenzoyl)-Piperidine, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.