Description

Benzenepropanamide, 4-Fluoro- is a specialized fluorinated aromatic amide building block of significant interest in advanced organic synthesis. Its core value lies in the strategic introduction of a fluorine atom onto the phenyl ring, which can dramatically alter the physicochemical and biological properties of target molecules. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorine atom enhances lipophilicity, metabolic stability, and biological activity.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated aromatic components in advanced electronic materials, contributing to improved thermal stability and electro-optical performance.
• Peptidomimetics & Bio-conjugation: The propanamide side chain makes it useful for constructing peptide analogs or for use in linker chemistry for bioconjugation applications.
• Chemical Research & Development: Employed in academic and industrial R&D settings for method development, structure-activity relationship (SAR) studies, and exploring new fluorination chemistries.

Basic Information

Product Name	Benzenepropanamide, 4-Fluoro-
CAS No.	25468-67-1
Molecular Formula	C9H10FNO
Molecular Weight	167.18 g/mol
Synonyms	4-Fluorobenzylacetamide; 4-Fluoro-β-phenylpropionamide; 3-(4-Fluorophenyl)propanamide; 4-Fluorohydrocinnamamide; p-Fluorobenzylacetamide; 4-Fluorodihydrocinnamamide; 3-(p-Fluorophenyl)propanamide; 25468-67-1
EINECS	Contact for details

Quality Control

Our Benzenepropanamide, 4-Fluoro- is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the material under an inert atmosphere or in a desiccator for long-term preservation to prevent moisture uptake. Recommended storage temperature: 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.