Description

Z-3-Cyclohexyl-L-Alanine is a non-proteinogenic amino acid derivative featuring a cyclohexyl side chain, which imparts unique conformational and lipophilic properties. This compound is a valuable chiral building block, primarily used in the synthesis of peptides and peptidomimetics to enhance metabolic stability and modulate biological activity. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing novel therapeutic agents, enzyme inhibitors, and as a key intermediate in medicinal chemistry.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, especially protease inhibitors and receptor antagonists.
• Peptide Synthesis: Used to incorporate conformational constraints and improve the lipophilicity and bioavailability of synthetic peptides.
• Medicinal Chemistry Research: Serves as a building block for creating compound libraries and studying structure-activity relationships (SAR).
• Bioconjugation: Can be utilized in the preparation of labeled compounds or antibody-drug conjugates (ADCs) due to its functional groups.
• Chemical Biology Probes: Employed in the design of probes to study enzyme mechanisms and protein-protein interactions.
• Agrochemical Research: Potential intermediate in the synthesis of advanced, biologically active crop protection agents.

Basic Information

Product Name	Z-3-Cyclohexyl-L-Alanine
CAS No.	25341-42-8
Molecular Formula	C₁₆H₂₁NO₄
Molecular Weight	291.34 g/mol
Synonyms	N-Carbobenzoxy-3-cyclohexyl-L-alanine; Z-3-Cyclohexyl-L-alanine; (S)-2-(((Benzyloxy)carbonyl)amino)-3-cyclohexylpropanoic acid; Nα-Cbz-3-cyclohexyl-L-alanine; N-Cbz-3-cyclohexyl-L-alanine; CBZ-3-Cyclohexyl-L-alanine; Z-3-Cyclohexylalanine; L-Alanine, N-[(phenylmethoxy)carbonyl]-3-cyclohexyl-
EINECS	Contact for details

Quality Control

Our Z-3-Cyclohexyl-L-Alanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.