Description

Bis(4-Fluorophenyl)Phosphine CAS NO 25186-17-8 is a specialized organophosphorus compound featuring two fluorinated aromatic rings, serving as a key intermediate in advanced chemical synthesis. Its primary value lies in its role as a versatile ligand and building block for constructing complex molecular architectures, particularly in the development of pharmaceuticals and functional materials. This high-purity chemical is essential for research and production facilities in the pharmaceutical, agrochemical, and materials science industries seeking to develop novel active ingredients and catalysts.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system disorders.
• Catalyst Ligand: Used as a ligand in transition metal catalysis for cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Agrochemical Synthesis: Serves as a building block for developing new generation herbicides and pesticides with enhanced efficacy.
• Material Science Research: Employed in the creation of novel organic electronic materials, such as ligands for phosphorescent OLED emitters.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new organophosphorus chemistry and reaction pathways.
• Liquid Crystal & Polymer Additive: Can be utilized in the synthesis of specialty monomers and additives for high-performance polymers.

Basic Information

Product Name	Bis(4-Fluorophenyl)Phosphine
CAS No.	25186-17-8
Molecular Formula	C12H9F2P
Molecular Weight	222.17 g/mol
Synonyms	Bis(p-Fluorophenyl)Phosphine; Di(4-fluorophenyl)phosphine; (4-Fluorophenyl)2PH; Phosphinous acid, bis(4-fluorophenyl)-; 4,4'-Difluorodiphenylphosphine; 1,1'-(Phosphinylidene)bis[4-fluorobenzene]; P,P-Bis(4-fluorophenyl)phosphine
EINECS	Contact for details

Quality Control

Our Bis(4-Fluorophenyl)Phosphine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from strong bases and oxidizing agents. Due to its sensitivity, minimize exposure to air and moisture during handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.