Description

1-Cbz-Pyrrolidine is a versatile and high-purity chemical building block, specifically an N-Carbobenzyloxy-protected pyrrolidine derivative. This compound is essential for advanced organic synthesis, particularly in the pharmaceutical sector, where it serves as a key intermediate for constructing complex molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system.
• Peptide Synthesis: Used as a protected amine component in solid-phase and solution-phase peptide chemistry to prevent unwanted side reactions.
• Heterocyclic Chemistry: Serves as a foundational scaffold for constructing more complex nitrogen-containing heterocycles with biological activity.
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, and insecticides that require specific pyrrolidine-based structures.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Material Science: Acts as a monomer or precursor in the synthesis of specialized polymers and functional materials.

Basic Information

Product Name	1-Cbz-Pyrrolidine
CAS No.	25070-74-0
Molecular Formula	C₁₂H₁₅NO₂
Molecular Weight	205.25 g/mol
Synonyms	1-(Benzyloxycarbonyl)pyrrolidine; N-Carbobenzyloxypyrrolidine; N-Cbz-Pyrrolidine; Pyrrolidine, 1-[(phenylmethoxy)carbonyl]-; 1-[(Benzyloxy)carbonyl]pyrrolidine; N-Benzyloxycarbonylpyrrolidine; Z-Pyrrolidine; NSC 3349
EINECS	Contact for details

Quality Control

Our 1-Cbz-Pyrrolidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.