Description

1-Indancarbonitrile, 3A,4,7,7A-Tetrahydro-2-Imino-, Stereoisomer (8Ci) is a specialized, high-purity chemical intermediate featuring a unique bicyclic nitrile-imine structure. This compound is valued for its stereochemical specificity, which is critical for synthesizing enantiomerically pure products in advanced pharmaceutical research. It serves as a key building block for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a stereodefined scaffold for constructing enantiomerically pure molecules in medicinal chemistry.
• Chemical Research: Serves as a valuable reagent in academic and industrial R&D for exploring new synthetic methodologies.
• Agrochemical Development: Potential intermediate for creating novel, stereospecific pesticides and herbicides.
• Material Science: Investigated as a monomer or precursor for specialty polymers with specific optical or mechanical properties.

Basic Information

Product Name	1-Indancarbonitrile, 3A,4,7,7A-Tetrahydro-2-Imino-, Stereoisomer (8Ci)
CAS No.	25050-75-3
Molecular Formula	C10H12N2
Molecular Weight	160.22 g/mol
Synonyms	1H-Indene-1-carbonitrile, 2,3,3a,4,7,7a-hexahydro-2-imino- (9CI); 2-Imino-2,3,3a,4,7,7a-hexahydro-1H-indene-1-carbonitrile; 3a,4,7,7a-Tetrahydro-1H-indene-1-carbonitrile, 2-imino-; Hexahydro-2-imino-1H-indene-1-carbonitrile; Stereoisomer of 25050-75-3; (R)- or (S)-1-Indancarbonitrile derivative; Bicyclo[4.3.0]nonane nitrile-imine intermediate
EINECS	Contact for details

Quality Control

Our 1-Indancarbonitrile, 3A,4,7,7A-Tetrahydro-2-Imino-, Stereoisomer (8Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and stereochemical composition.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be sensitive to prolonged exposure to moisture and air; consider storage under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.