Description

Methyl Hexahydro-α-Methyl-1H-Azepine-1-Propionate Hydrochloride is a high-purity organic salt with the CAS registry number 25027-58-1. This compound serves as a critical advanced intermediate in the synthesis of complex pharmaceutical molecules, offering a defined stereochemical center for building chiral complexity. It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of new active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug research.
• Fine Chemical Synthesis: Used as a chiral synthon for constructing complex molecular architectures in custom synthesis and process development.
• Agrochemical Research: Potential intermediate in the development of new generation pesticides and herbicides requiring specific stereochemistry.
• Academic & R&D: Serves as a valuable reagent for methodological studies in organic chemistry, asymmetric synthesis, and catalysis.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of specialty chemicals.

Basic Information

Product Name	Methyl Hexahydro-α-Methyl-1H-Azepine-1-Propionate Hydrochloride
CAS No.	25027-58-1
Molecular Formula	C12H23NO2 • HCl
Molecular Weight	249.78 g/mol (Free base: 213.32 g/mol)
Synonyms	1H-Azepine-1-propanoic acid, hexahydro-α-methyl-, methyl ester, hydrochloride; Methyl 1-(2-methoxy-2-oxoethyl)-2-methylazepane-1-carboxylate hydrochloride; Methyl 2-methyl-1-(2-methoxy-2-oxoethyl)azepane-1-carboxylate hydrochloride; α-Methylhexahydro-1H-azepine-1-propionic acid methyl ester hydrochloride; Methyl 2-methylazepane-1-acetate hydrochloride (common name); Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our Methyl Hexahydro-α-Methyl-1H-Azepine-1-Propionate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.