Description

4-(Methylsulfonyl)Phenylacetonitrile is a versatile and high-value organic intermediate characterized by its phenylacetonitrile core functionalized with a methylsulfonyl group. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. Industries that need it include pharmaceutical developers, agrochemical manufacturers, and specialty chemical producers focused on creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system disorders and inflammation.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the methylsulfonyl group contributes to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals due to its electron-withdrawing sulfone moiety.
• Custom Synthesis and Contract Manufacturing: A valuable substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-(Methylsulfonyl)Phenylacetonitrile
CAS No.	25025-07-4
Molecular Formula	C9H9NO2S
Molecular Weight	195.24 g/mol
Synonyms	p-(Methylsulfonyl)phenylacetonitrile; 4-(Methanesulfonyl)benzyl cyanide; (4-Methylsulfonylphenyl)acetonitrile; 2-[4-(Methylsulfonyl)phenyl]acetonitrile; 4-Methylsulfonylbenzyl cyanide; 25025-07-4; 4-Methanesulfonylphenylacetonitrile
EINECS	Contact for details

Quality Control

Our 4-(Methylsulfonyl)Phenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	110 - 114 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.