Description

(3-Bromo-Phenyl)-Oxo-Acetonitrile is a versatile brominated aromatic nitrile building block of significant interest in advanced organic synthesis. Its value lies in its bifunctional reactivity, where the bromoaryl group enables cross-coupling reactions and the oxo-acetonitrile moiety serves as a key precursor for heterocyclic systems. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, including active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides and fungicides, leveraging its halogenated aromatic core.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and as a precursor for pyrazoles, isoxazoles, and other nitrogen-containing heterocycles.
• Chemical Research & Development: Essential for academic and industrial R&D exploring new reaction methodologies and compound libraries.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized colorants and photographic chemicals.

Basic Information

Product Name	(3-Bromo-Phenyl)-Oxo-Acetonitrile
CAS No.	24999-51-7
Molecular Formula	C8H4BrNO
Molecular Weight	210.03 g/mol
Synonyms	2-Oxo-2-(3-bromophenyl)acetonitrile; 3-Bromobenzoyl cyanide; (3-Bromobenzoyl)formonitrile; α-Oxo-3-bromobenzeneacetonitrile; 3-Bromophenacyl cyanide; 3-Bromo-α-oxobenzeneacetonitrile; 2-(3-Bromophenyl)-2-oxoacetonitrile; 3-Bromobenzoylformonitrile
EINECS	Contact for details

Quality Control

Our (3-Bromo-Phenyl)-Oxo-Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.