Description

H-L-Lys(Boc)-Nh2 is a protected amino acid derivative, specifically Nε-Boc-L-lysine amide, widely used as a critical building block in peptide synthesis. This compound matters for its role in facilitating the controlled elongation of peptide chains, where the Boc (tert-butoxycarbonyl) group provides orthogonal protection for the lysine side chain. Pharmaceutical researchers, peptide manufacturers, and biotechnology companies need it for the development of therapeutic peptides, diagnostic agents, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the incorporation of lysine residues with protected side chains.
• Solution-Phase Peptide Chemistry: Used in the synthesis of complex peptides and peptidomimetics in solution.
• Pharmaceutical Intermediate: Building block for active pharmaceutical ingredients (APIs) in peptide-based drugs targeting metabolic, oncological, and infectious diseases.
• Bioconjugation and Linker Chemistry: Serves as a precursor for creating cross-linkers or functionalized molecules for antibody-drug conjugates (ADCs) and other bioconjugates.
• Research & Development: Essential reagent in academic and industrial R&D for studying protein-protein interactions and developing novel bioactive compounds.
• Combinatorial Library Synthesis: Used to generate diverse libraries of peptide compounds for high-throughput screening in drug discovery.

Basic Information

Product Name	H-L-Lys(Boc)-Nh2
CAS No.	24828-96-4
Molecular Formula	C11H23N3O3
Molecular Weight	245.32 g/mol
Synonyms	Nε-Boc-L-lysine amide; (S)-2,6-Diamino-N-[(2-methyl-2-propanyl)oxy]carbonyl]hexanamide; Boc-Lys-NH2; Boc-L-Lysine amide; Nα-Boc-L-lysine amide; H-Lys(Boc)-NH2; N6-[(1,1-Dimethylethoxy)carbonyl]-L-lysine amide; L-Lysine, N2-[(1,1-dimethylethoxy)carbonyl]-, amide
EINECS	Contact for details

Quality Control

Our H-L-Lys(Boc)-Nh2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive identification tests, to ensure compliance with high-purity standards for pharmaceutical and research applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]D20	+15.0° to +18.0° (c=1 in AcOH)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.