Description

Cladribine Related Compound A (2-Methoxy-2'-Deoxyadenosine) is a high-purity chemical reference standard and synthetic intermediate of significant importance in pharmaceutical research and development. This compound is critical for analytical method development, impurity profiling, and quality control processes in the production of active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical manufacturers engaged in the synthesis and characterization of nucleoside analogs and related therapeutic agents.

Application

• Pharmaceutical Reference Standard: Serves as a certified impurity standard for the analysis and quality control of Cladribine API and related drug substances.
• Analytical Research: Used in method development and validation for HPLC, LC-MS, and other chromatographic techniques to identify and quantify related substances.
• Process Chemistry: Acts as a key intermediate or a model compound in the research-scale synthesis of modified nucleosides and antiviral agents.
• Biochemical Studies: Employed in enzymatic and metabolic pathway research to study the behavior of deoxyadenosine analogs.
• Academic Research: Utilized in universities and research institutes for studies in medicinal chemistry, oncology, and nucleotide biochemistry.

Basic Information

Product Name	Cladribine Related Compound A (2-Methoxy-2'-Deoxyadenosine)
CAS No.	24757-70-8
Molecular Formula	C11H15N5O4
Molecular Weight	281.27 g/mol
Synonyms	2-Methoxy-2'-deoxyadenosine; 2'-Deoxy-2-methoxyadenosine; 9-(2-Deoxy-2-methoxy-β-D-erythro-pentofuranosyl)adenine; 2-Methoxy-2'-deoxyadenosine; Cladribine Impurity A; 2'-Deoxy-2-O-methyladenosine; 2-Methoxy-2'-deoxyadenosine (Cladribine Related Compound A); 2'-Deoxy-2-methoxyadenosine (Cladribine Impurity)
EINECS	Contact for details

Quality Control

Our Cladribine Related Compound A is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC purity analysis, identity confirmation (IR, NMR), and residual solvent screening, to ensure it meets the stringent requirements for reference standards and pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all test results against established specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.