Description

2-Cyano-N-[4-(Trifluoromethyl)Phenyl]Acetamide is a specialized organic compound featuring a cyanoacetamide core substituted with a trifluoromethylphenyl group. This structure makes it a valuable high-purity chemical intermediate for advanced synthesis in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients. The compound's properties are critical for constructing complex molecules where the trifluoromethyl moiety can enhance metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the production of specialized polymers and advanced organic materials.
• Chemical Synthesis: Versatile intermediate for creating libraries of compounds in medicinal chemistry for high-throughput screening and structure-activity relationship (SAR) studies.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Cyano-N-[4-(Trifluoromethyl)Phenyl]Acetamide
CAS No.	24522-30-3
Molecular Formula	C10H7F3N2O
Molecular Weight	228.17 g/mol
Synonyms	2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide; N-(4-Trifluoromethylphenyl)-2-cyanoacetamide; 2-Cyano-2-(4-trifluoromethylphenylamino)acetic acid amide; 2-Cyanoacetamide, N-[4-(trifluoromethyl)phenyl]-; Acetamide, 2-cyano-N-[4-(trifluoromethyl)phenyl]-; α-Cyano-4-(trifluoromethyl)acetanilide; 4-Trifluoromethylphenylcyanoacetamide
EINECS	Contact for details

Quality Control

Our 2-Cyano-N-[4-(Trifluoromethyl)Phenyl]Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.