Description

Disodium 3-[5-[(3-Carboxylato-2,4,6-Triiodo-Phenyl)Carbamoyl]Pentanoyl Amino]-2,4,6-Triiodo-Benzoate is a high-purity, iodinated organic compound primarily utilized as a key intermediate in the synthesis of X-ray contrast media. Its molecular structure, featuring multiple iodine atoms, is engineered to provide excellent radiopacity, making it a critical building block for diagnostic imaging agents. This product is essential for pharmaceutical manufacturers and advanced chemical synthesis facilities focused on developing non-ionic, low-osmolar contrast media for enhanced patient safety and diagnostic clarity.

Application

• Pharmaceutical Intermediate: Primary use as a precursor in the synthesis of non-ionic X-ray contrast agents like iopamidol, iohexol, and ioversol.
• Diagnostic Imaging: Serves as a fundamental component for contrast media used in computed tomography (CT), angiography, and urography.
• Research & Development: Used in academic and industrial R&D for developing novel iodinated contrast molecules with improved safety profiles.
• Chemical Synthesis: Acts as a specialized intermediate for creating complex, tri-iodinated benzene derivatives for various advanced organic syntheses.
• GMP Manufacturing: Supplied for use in Good Manufacturing Practice (GMP) environments for the production of approved active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Disodium 3-[5-[(3-Carboxylato-2,4,6-Triiodo-Phenyl)Carbamoyl]Pentanoyl Amino]-2,4,6-Triiodo-Benzoate
CAS No.	24360-85-8
Molecular Formula	C20H13I6N2Na2O7
Molecular Weight	1259.74 g/mol
Synonyms	Disodium 5-[N-(3-Carboxy-2,4,6-triiodophenyl)carbamoyl]pentanamido]-2,4,6-triiodoisophthalate; Iopamidol Impurity; Iopamidol Intermediate; Iohexol Related Compound; 3,5-Bis(acetylamino)-2,4,6-triiodobenzoic Acid Disodium Salt Derivative; 5-Acetamido-2,4,6-triiodo-N-(2-hydroxyethyl)isophthalamic Acid Intermediate; Contrast Media Intermediate C21; AD-01 (Research Code)
EINECS	Contact for details

Quality Control

Our Disodium 3-[5-[(3-Carboxylato-2,4,6-Triiodo-Phenyl)Carbamoyl]Pentanoyl Amino]-2,4,6-Triiodo-Benzoate is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development with custom purity grades, including materials suitable for GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.