Description

S-Adenosyl-L-Methionine Chloride Salt is a critical biochemical cofactor and methyl group donor essential for numerous cellular processes. This high-purity compound is vital for research and development in life sciences and pharmaceutical manufacturing, where precise biochemical activity is required. It is primarily utilized by biotech companies, pharmaceutical R&D laboratories, and manufacturers of nutraceutical intermediates seeking a reliable, high-quality source for enzymatic studies and advanced synthesis.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of advanced therapeutic agents and investigational drugs.
• Biochemical Research: Essential cofactor for studying methylation reactions, enzyme kinetics (methyltransferases), and cellular metabolism pathways.
• Nutraceutical Formulation: Used in the development of high-grade dietary supplements targeting liver health, joint function, and mood support.
• Diagnostic Reagent Manufacturing: Component in enzymatic assay kits and diagnostic reagents for clinical and research laboratories.
• Cell Culture & Microbiology: Supplement in specialized cell culture media to support specific metabolic functions in eukaryotic cells.

Basic Information

Product Name	S-Adenosyl-L-Methionine Chloride Salt
CAS No.	24346-00-7
Molecular Formula	C15H22N6O5S+·Cl-
Molecular Weight	434.89 g/mol
Synonyms	SAMe; AdoMet; S-Adenosylmethionine Chloride; Adenosylmethionine Chloride; SAM Chloride; (3S)-5'-[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxyadenosine Chloride; L-Methionine, S-[5'-deoxyadenosin-5'-yl]-, chloride (1:1); Acebrosam
EINECS	Contact for details

Quality Control

Our S-Adenosyl-L-Methionine Chloride Salt is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for research and industrial use. Certificates of Analysis (COA) documenting purity, potency, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to Standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	+48° to +52° (c=1 in 0.1N HCl)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents	Meets ICH Guidelines
Bacterial Endotoxins	< 0.5 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.