Description

2-[[3-(n-Methylpropanoylamino)-2,4,6-Triiodophenyl]Oxy]Hexanoic Acid is a specialized iodinated organic compound with a complex molecular structure. This chemical is of significant commercial interest due to its role as a key intermediate in the synthesis of advanced X-ray contrast media and diagnostic imaging agents. It is primarily required by pharmaceutical manufacturers and fine chemical producers engaged in the development of non-ionic, low-osmolar contrast agents for enhanced medical imaging safety and efficacy. The compound's precise synthesis and high purity are critical for ensuring the performance and regulatory compliance of the final pharmaceutical product.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of non-ionic iodinated contrast media used in computed tomography (CT) scans, angiography, and urography.
• Diagnostic Agent Synthesis: Used in the research and production of advanced diagnostic imaging compounds that offer improved patient tolerance and safety profiles.
• Fine Chemical Manufacturing: Serves as a high-value intermediate for custom synthesis and contract manufacturing organizations (CMOs) specializing in complex organic molecules.
• Research & Development: Utilized in academic and industrial R&D settings for developing new contrast agents with enhanced biodistribution and clearance properties.
• Radiopharmaceutical Precursor: Potential use in the development of compounds for other imaging modalities, though primarily for X-ray/CT contrast.

Basic Information

Product Name	2-[[3-(n-Methylpropanoylamino)-2,4,6-Triiodophenyl]Oxy]Hexanoic Acid
CAS No.	24340-27-0
Molecular Formula	C16H21I3N2O4
Molecular Weight	662.06 g/mol
Synonyms	2-[[3-(N-Methylbutyramido)-2,4,6-triiodophenoxy]hexanoic Acid; Iopamidol Intermediate; Iopamidol Related Compound; 3-(N-Methylbutyramido)-2,4,6-triiodophenyl 2-ethylbutyrate derivative; Hexanoic acid, 2-[[3-[(1-oxobutyl)methylamino]-2,4,6-triiodophenoxy]-; Iodinated contrast media intermediate; N-Methyl-3-butyramido-2,4,6-triiodophenyl 2-ethylbutyrate acid
EINECS	Contact for details

Quality Control

Our production of 2-[[3-(n-Methylpropanoylamino)-2,4,6-Triiodophenyl]Oxy]Hexanoic Acid adheres to stringent quality systems suitable for pharmaceutical intermediate manufacturing. Each batch is subjected to rigorous analytical testing, including HPLC for purity and related substance profiling, to ensure compliance with internal specifications and customer requirements. Certificates of Analysis (COA) documenting identity, assay, and impurity levels are provided with every shipment. We support audits and can tailor quality protocols to align with cGMP, ICH Q7, and other relevant regulatory guidelines for active pharmaceutical ingredient (API) intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.