Description

2-[3-(n-Methylpropionylamino)-2,4,6-Triiodophenoxy]Butyric Acid is a specialized, high-purity iodinated organic compound primarily used as a key intermediate in pharmaceutical synthesis. This compound matters for its critical role in the development of advanced X-ray contrast media, where its triiodinated aromatic structure is essential for providing high radiopacity. Pharmaceutical manufacturers and advanced chemical research facilities need this high-grade intermediate to ensure the quality and efficacy of final diagnostic imaging agents.

Application

• Primary Intermediate for X-ray Contrast Media: Serves as a crucial building block in the synthesis of non-ionic, low-osmolar contrast agents used in computed tomography (CT) and angiography.
• Pharmaceutical Research & Development: Used in the discovery and development of new iodinated diagnostic compounds with improved safety and imaging profiles.
• Advanced Organic Synthesis: Acts as a versatile intermediate for creating complex molecules containing iodine, useful in various specialty chemical applications.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical manufacturing.

Basic Information

Product Name	2-[3-(n-Methylpropionylamino)-2,4,6-Triiodophenoxy]Butyric Acid
CAS No.	24340-24-7
Molecular Formula	C14H17I3N2O4
Molecular Weight	677.01 g/mol
Synonyms	2-[3-(N-Methylpropionamido)-2,4,6-triiodophenoxy]butanoic acid; 2-[3-(N-Methylpropionylamino)-2,4,6-triiodophenoxy]butyric acid; Butyric acid, 2-[3-(methylpropionylamino)-2,4,6-triiodophenoxy]-; Iopamidol Intermediate; Iopamidol Related Compound; N-Methyl-2-[2,4,6-triiodo-3-(propionylamino)phenoxy]butanamide precursor; Triiodophenoxy Butyric Acid Derivative
EINECS	Contact for details

Quality Control

Our 2-[3-(n-Methylpropionylamino)-2,4,6-Triiodophenoxy]Butyric Acid is manufactured under strict quality systems suitable for pharmaceutical intermediate applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications. Certificates of Analysis (COA) with full traceability are provided and can be tailored to support GMP, ICH Q7, and relevant pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.