Description

2-[3-(n-Ethylacetylamino)-2,4,6-Triiodophenoxy]Valeric Acid is a high-purity iodinated organic compound, serving as a critical intermediate in the synthesis of modern X-ray contrast media. Its precise chemical structure is essential for ensuring the safety and efficacy of the final diagnostic agents. This product is primarily required by pharmaceutical manufacturers and advanced research institutions developing next-generation non-ionic contrast media for enhanced patient safety and diagnostic clarity.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing non-ionic, low-osmolar X-ray contrast agents like Iopamidol, Ioversol, and Ioxilan.
• Medical Imaging Research: Used in R&D for developing novel iodinated contrast media with improved pharmacokinetic profiles.
• Contrast Agent Formulation: Integral in the production chain for final injectable formulations used in computed tomography (CT) and angiography.
• Chemical Synthesis: Serves as a versatile intermediate for further chemical modifications to create derivatives with specific properties.
• Quality Control Reference Standard: Employed as a certified reference material (CRM) for analytical method development and validation in pharmaceutical QC labs.

Basic Information

Product Name	2-[3-(n-Ethylacetylamino)-2,4,6-Triiodophenoxy]Valeric Acid
CAS No.	24340-18-9
Molecular Formula	C15H19I3N2O4
Molecular Weight	704.04 g/mol
Synonyms	5-[2,4,6-Triiodo-3-(N-ethylacetamido)phenoxy]valeric Acid; Iopamidol Intermediate; Ioversol Intermediate; 2-[3-(Acetylethylamino)-2,4,6-triiodophenoxy]pentanoic Acid; AEITV; N-Ethyl-2',4',6'-triiodo-3'-(4-carboxybutoxy)acetanilide; 24340-18-9; Valeric acid, 2-[3-(N-ethylacetamido)-2,4,6-triiodophenoxy]-
EINECS	Contact for details

Quality Control

Our 2-[3-(n-Ethylacetylamino)-2,4,6-Triiodophenoxy]Valeric Acid is manufactured under strict quality management systems. We provide material that meets stringent specifications suitable for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch to ensure traceability and compliance with cGMP and ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 10 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.