Description

2-[3-(n-Methylacetylamino)-2,4,6-Triiodophenoxy]Propionic Acid is a high-purity iodinated organic compound primarily utilized as a key intermediate in the synthesis of X-ray contrast media. Its precise chemical structure, featuring a triiodinated aromatic ring, is critical for imparting the radiopacity required in diagnostic imaging agents. This product is essential for pharmaceutical manufacturers and advanced research facilities developing non-ionic, low-osmolar contrast agents for enhanced patient safety and diagnostic clarity.

Application

• Pharmaceutical Intermediate: Primary building block for synthesizing non-ionic X-ray contrast agents like iopamidol, iohexol, and ioversol.
• Diagnostic Imaging Research: Used in R&D for developing next-generation contrast media with improved safety profiles and imaging characteristics.
• Contrast Agent Formulation: A critical precursor in the production of injectable formulations for computed tomography (CT) and angiography.
• Chemical Synthesis: Serves as a specialized intermediate for creating other iodinated aromatic compounds in organic chemistry.
• Quality Control Reference Standard: Employed as a high-purity reference material in analytical laboratories for method development and validation.

Basic Information

Product Name	2-[3-(n-Methylacetylamino)-2,4,6-Triiodophenoxy]Propionic Acid
CAS No.	24340-13-4
Molecular Formula	C12H12I3NO4
Molecular Weight	662.94 g/mol
Synonyms	N-Methyl-2,4,6-triiodo-3-[(2-methoxyethoxy)carbonyl]acetamilide; 3-Acetamido-2,4,6-triiodo-5-[2-(methoxycarbonyl)ethoxy]benzoic Acid Methyl Ester (related ester); Iopamidol Intermediate; Iohexol Intermediate; 5-Acetamido-2,4,6-triiodo-N-methylisophthalamic Acid Derivative; ATMP; Contrast Media Intermediate CMI-24340
EINECS	Contact for details

Quality Control

Our 2-[3-(n-Methylacetylamino)-2,4,6-Triiodophenoxy]Propionic Acid is manufactured under strict quality systems suitable for pharmaceutical intermediate applications. Production adheres to cGMP (current Good Manufacturing Practice) guidelines, and each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with stringent internal specifications designed to meet the exacting requirements of our global pharmaceutical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 10 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.