Description

(E)-2-Bromo-2-Butenenitrile is a versatile halogenated alkenyl nitrile building block of significant interest in synthetic organic chemistry. Its value lies in its bifunctional reactivity, featuring both an electrophilic bromoalkene and a nitrile group, making it a key precursor for constructing complex molecular frameworks. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop active ingredients, functional polymers, and novel chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing vinyl halide or cyanoethyl motifs.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides, leveraging its reactivity to create novel heterocyclic compounds.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of specialty polymers, resins, and liquid crystal materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Heck), Michael additions, and cyclization reactions to form complex organic structures in R&D laboratories.
• Chemical Research: A valuable tool for academic and industrial chemists exploring new reaction methodologies and synthesizing libraries of compounds for screening.

Basic Information

Product Name	(E)-2-Bromo-2-Butenenitrile
CAS No.	24325-95-9
Molecular Formula	C4H4BrN
Molecular Weight	145.98 g/mol
Synonyms	trans-2-Bromo-2-butenenitrile; (E)-2-Bromo-2-butenenitrile; 2-Bromo-2-butenenitrile; 2-Butenenitrile, 2-bromo-, (E)-; Bromocrotononitrile; trans-β-Bromocrotononitrile; (E)-1-Bromo-1-cyano-1-propene
EINECS	Contact for details

Quality Control

Our (E)-2-Bromo-2-Butenenitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its light-sensitive nature and reactivity, it is recommended to store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.