Description

n-α-T-Boc-L-Glutamine Dicyclohexylammonium Salt is a protected amino acid derivative widely used as a crucial building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates to ensure the integrity and yield of complex peptide sequences. It is primarily utilized by the pharmaceutical, biotechnology, and research sectors for the development of therapeutic peptides, APIs, and novel biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of glutamine residues while protecting the side chain amide functionality.
• Solution-Phase Peptide Chemistry: Used in the synthesis of peptide fragments and conjugates where Boc (tert-butoxycarbonyl) protection strategy is employed.
• Pharmaceutical Research & Development: Serves as a critical raw material in the R&D of peptide-based drugs, hormones, and diagnostic agents.
• Bioconjugation: Facilitates the site-specific modification of peptides and proteins for creating labeled probes or drug conjugates.
• Combinatorial Chemistry: Used in libraries for high-throughput screening to discover new bioactive peptide leads.
• Academic & Institutional Research: Employed in biochemical studies investigating protein structure, function, and peptide interactions.

Basic Information

Product Name	n-α-T-Boc-L-Glutamine Dicyclohexylammonium Salt
CAS No.	24277-35-8
Molecular Formula	C₂₀H₃₇N₃O₅
Molecular Weight	399.53 g/mol
Synonyms	Boc-Gln-OH·DCHA; N-α-tert-Butoxycarbonyl-L-glutamine Dicyclohexylamine Salt; (2S)-5-Amino-2-[[(2-methylpropan-2-yl)oxycarbonyl]amino]-5-oxopentanoic acid - N,N-dicyclohexylamine (1:1); L-Glutamine, N-[(1,1-dimethylethoxy)carbonyl]-, compd. with N,N-dicyclohexylamine (1:1); Boc-L-Glutamine DCHA Salt; Boc-Gln-DCHA; tert-Butoxycarbonyl-L-glutamine dicyclohexylammonium salt
EINECS	Contact for details

Quality Control

Our n-α-T-Boc-L-Glutamine Dicyclohexylammonium Salt is produced and tested under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support requirements for cGMP manufacturing upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	-15.0° to -18.0° (c=1 in DMF)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.